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PHOSPHOMYCIN DISODIUM SALT ANTIBACTERIAL MURA INHIBITOR (C005B-439020)

Catalog No.
C005B-439020
Manufacturer No.
P5396-5G
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
GM

Application Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae . It is used to treat uncomplicated urinary tract infections.

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Application

Phosphomycin, also known as Fosfomycin, is an antibiotic produced by Streptomyces fradiae. It is used to treat uncomplicated urinary tract infections. It is used for susceptibility studies of Klebsiella pneumoniae and to study in vitro susceptibility testing procedures for fosfomycin tromethamine.

Biochem/physiol Actions

Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.

Other Notes

1g,5g,50g

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

UPC:
12352307
Condition:
New
HazmatClass:
No
MPN:
P5396-5G

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