PHENYLHYDRAZINE HYDROCHLORIDE 99+% (C005B-051180)

Application

Phenylhydrazine hydrochloride is used in the examination of tyrosine phosphorylation of Janus protein tyrosine kinase (JAKs) in the EPO-responsive normal erythroblastoid cells of anemic mice.

Biochem/physiol Actions

Phenylhydrazine hydrochloride causes acute hemolysis when injected intraperitoneally in to wild-type and Hp and Hx single-null mice. It suppresses the horseradish peroxide (HRP) residual activity in tissue sections of animals.

Preparation Note

50 gm of Phenylhydrazine hydrochloride dissolves in 1 mL of water to yield a clear, very faint yellow solution.

Molecular Weight: 144.60. Empirical Formula: C₆H₈N₂ · HCl. linearFormula: C₆H₅NHNH₂ · HCl. Quality Level: 200. Assay: ≥. 99%. form: solid. mp: 250-254 . °C (dec.) (lit.). solubility: H₂O: soluble 50 . mg/mL. SMILES string: Cl[H].NNc1ccccc1. InChI: 1S/C6H8N2.ClH/c7-8-6-4-2-1-3-5-6. /h1-5,8H,7H2. 1H. InChI key: JOVOSQBPPZZESK-UHFFFAOYSA-N. Pictograms: GHS06,GHS08,GHS09. Signal Word: Danger. Hazard Statements: H301 + H311 + H331 - H315 - H317 - H319 - H341 - H350 - H372 - H400. Precautionary Statements: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1. Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.