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pf-00835231 (c09-1017-405)

PF-00835231 (C007B-248652)

Catalog No.
C007B-248652
Manufacturer No.
P414478-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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InformationPF-00835231 PF-00835231 is a 3CL pro (M pro ) inhibitor that may targets SARS-CoV-2 protease 3CL pro as a potential new treatment for COVID-19.Targets3CLproIn vitroA time-of-drug-addition approach delineates the timing of early SARS-CoV-2

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InformationPF-00835231 PF-00835231 is a 3CL pro (M pro ) inhibitor that may targets SARS-CoV-2 protease 3CL pro as a potential new treatment for COVID-19.Targets3CLproIn vitroA time-of-drug-addition approach delineates the timing of early SARS-CoV-2 life cycle steps in A549+ACE2 cells and validates PF-00835231/'s early time of action. In a model of the human polarized airway epithelium, PF-00835231 potently inhibits SARS-CoV-2 at low micromolar concentrations. PF-00835231 exhibits the potential as an effective SARS-CoV-2 antiviral.Cell Research(from reference)Cell lines：A549 cells, human airway epithelial cultures (HAEC) Concentrations：1 nM-10 μM Incubation Time：0-4 h.

Specifications and Purity: ≥98%

Molecular Formula: C24H32N4O6

Molecular Weight: 472.53

PubChem CID: 11561899

Isomeric SMILES: CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO)NC(=O)C2=CC3=C(N2)C=CC=C3OC

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/P414478-SCI_4a13b93fae185df41078848809e99d9c.pdf

UPC:
41105331
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
P414478-25mg
CAS:
870153-29-0
Product Size:
25mg

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