PD-1/PD-L1-IN-14 (C007B-386288)

Catalog No.: C007B-386288
Manufacturer No.: P650673-5mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

PD-1/PD-L1-IN-14 (compound 17) is a bifunctional inhibitor of PD-1/PD-L1 interactions, with an IC 50 of 27.8 nM. PD-1/PD-L1-IN-14 (compound 17) inhibits PD-1/PD-L1 interactions and promotes dimerization, internalization, and degradation of PD-L1In VitroPD-1/PD-L1-IN-14 (compound 17) promotes cell-surface PD-L1 internalized into the cytosol and induces the degradation of PD-L1 in tumor cells through a lysosome-dependent pathway. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50： 27.8 nM (PD-1/PD-L1).

Molecular Formula: C24H24N4O2

Molecular Weight: 400.47

UPC:: 42191708
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: P650673-5mg
CAS:: 2499965-12-5
Product Size:: 5mg

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