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parp7-in-14 (c09-1165-551)

PARP7-IN-14 (C007B-387072)

Catalog No.
C007B-387072
Manufacturer No.
P659390-5mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.Appearance:SolidIn Vitro:PARP7-IN-14 (I-1) inhibits CT26 cell lines with the IC 50 value of 12.85 μM and shows some

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PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.Appearance:SolidIn Vitro:PARP7-IN-14 (I-1) inhibits CT26 cell lines with the IC 50 value of 12.85 μM and shows some anti-proliferative effect on tumors. PARP7-IN-14 (I-1) (0-4 μM) promotes mRNA expression levels of IFN-β and CXCL10 and induces a concentration-dependent increIn Vivo:PARP7-IN-14 (I-1) (p.o., 25-100mg/kg, twice daily, 14 days) significantly inhibits tumour growth in CT26 tumour-bearing mice, with a 67% reduction in mean tumour volume in mice treated with I-1 compared to controls, and does not cause weight loss or otheBiological Activity:PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.

Specifications and Purity: ≥98%

Molecular Formula: C21H24F6N8O2

Molecular Weight: 534.46

UPC:
51171703
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
P659390-5mg
Product Size:
5mg

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