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p38alpha/sapk2a (t106m) protein, active, 10 µg

P38A/SAPK2A(T106M) ACTIVE 10UG

Catalog No.
C005B-095737
Manufacturer No.
14-687
Manufacturer Name
Upstate
Quantity
10
Unit of Measure
UG

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N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione- agarose.

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General description

N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione- agarose.

Contains the gatekeeper mutation T160M in the ATP-binding domain. This mutation increases resistance to SB203580 as compared to the wild type sequence.

Product Source: Human, full-length p38α/SAPK2a containing the mutation T106M. Expressed in E. coli.

Quality

routinely evaluated by phosphorylation of MBP (13-104).

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

biological source: human. Quality Level: 100, 300. recombinant: expressed in E. coli. mol wt: Mw 67.7 . kDa. manufacturer/tradename: Upstate®. . technique(s): activity assay: suitable (kinase). NCBI accession no.: NM_001315.1, NM_139012.1, NM_139013.1, NM_139014.1. UniProt accession no.: Q16539. Gene Information: human ... MAPK14(1432). Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H317. Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364. Hazard Classifications: Skin Sens. 1. Storage Class Code: 10 - Combustible liquids. WGK: WGK 1.
UPC:
41106500
Condition:
New
HazmatClass:
No
MPN:
14-687
Temperature Control Device:
Yes

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