OXALYL CHLORIDE REAGENT GRADE 98% (C005B-442177)

General description

Oxalyl chloride is a versatile reagent in various chemical transformations, such as chlorination, dichlorination, oxidation, reduction, dehydration, decarboxylation, formylation, and ring cleavage of epoxides.

Application

Oxalyl chloride can be used as an oxidizing agent:

• To synthesize β, β′-diketodithioethers from β, β′-dihydroxydithioethers via Swern oxidation.
• In the DMSO-catalyzed Swern oxidation of primary amides or aldoximes to nitriles in the presence of triethylamine as a base.
• In the Moffatt-Swern oxidation of aryl allylic alcohols to halogenated unsaturated ketones in the presence of triethylamine.

Reactant involved in:

• Synthesis of N-heterocyclic ynones and ynediones, used to activate carboxylic acids
• Chlorination and halogenation
• Three-component [3+2] cycloadditions
• Reactions with organostannanes
• Synthesis of cyclopentenones
• Carbonylations, used as a carbonyl synthon