OXALYL CHLORIDE REAGENTPLUS >=99% (C005B-081045)

General description

Oxalyl chloride is a commonly used chlorinating reagent that can be prepared by the reaction of oxalic acid and phosphorus pentachloride.

Application

Oxalyl chloride may be used in the following processes:

• Preparation of Mosher′s acid chloride by reacting with Mosher′s acid in the presence of DMF.
• Activation of dimethyl sulfoxide for use in the oxidation of long-chain alcohols to carbonyls.
• Activation of α-keto carboxylic acids and N-heterocyclic carboxylic acids for alkynylation to form ynediones and N-heterocyclic ynones, respectively.

Suitable for the synthesis of acid chlorides used to produce liquid crystals.

Reactant involved in:

• Synthesis of N-heterocyclic ynones and ynediones, used to activate carboxylic acids
• Chlorination and halogenation
• Three-component [3+2] cycloadditions
• Reactions with organostannanes
• Synthesis of cyclopentenones
• Carbonylations, used as a carbonyl synthon

Packaging

The 5g, 25g and 100g units sold in the US are packaged in ampules.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Molecular Weight: 126.93. Empirical Formula: C₂Cl₂O₂. linearFormula: ClCOCOCl. vapor density: 4.4 (vs air). Quality Level: 200. vapor pressure: 150 mmHg ( 20 °C). product line: ReagentPlus^®. . Assay: ≥. 99%. form: liquid. reaction suitability: reagent type: oxidant. impurities: <. 10 . ppb Heavy metals. color: APHA: 0-150. refractive index: n20/D 1.429 (lit.). bp: 62-65 . °C (lit.). mp: −. 10-−. 8 . °C (lit.). density: 1.5 . g/mL . at 20 . °C (lit.). SMILES string: ClC(: O)C(Cl): O. InChI: 1S/C2Cl2O2/c3-1(5)2(4)6. InChI key: CTSLXHKWHWQRSH-UHFFFAOYSA-N. Pictograms: GHS02,GHS05,GHS06. Signal Word: Danger. Hazard Statements: H225 - H260 - H301 + H331 - H314. Precautionary Statements: P210 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - Water-react 1. Supp Hazards: EUH014 - EUH029 - EUH071. Storage Class Code: 4.3 - Hazardous materials, which set free flammable gases upon contact with water. WGK: WGK 1. Flash Point(F): 51.8 °F - closed cup. Flash Point(C): 11.0 °C - closed cup. Personal Protective Equipment: Faceshields, Gloves, Goggles.