OSMI-4 (C007B-397884)

Catalog No.: C007B-397884
Manufacturer No.: O414263-2mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationOSMI-4 OSMI-4 is an inhibitor of O-GlcNAc transferase (OGT) with EC50 of 3 μM in cells.TargetsOGT (Cell-free assay) 3 μM(EC50)In vitroOSMI-4 reduces O-GlcNAc levels almost completely by 5 μM. A decrease in HCF-1 cleavage products and the appearance of uncleaved HCF-1 is observed in cells treated with OSMI-4. OSMI-4 is a kind of structure-based evolution of small molecule OGT inhibitors with low nanomolar binding affinities. OSMI-4 exhibits a ~3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology.Cell Research(from reference)Cell lines：HEK293T cells Concentrations：5 μM, 10 μM, 20 μM Incubation Time：2 h, 8 h, 16 h, 24 h.

Specifications and Purity: ≥97%

Molecular Formula: C27H26ClN3O7S2

Molecular Weight: 604.09

PubChem CID: 137319721

UPC:: 42172000
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: O414263-2mg
CAS:: 2260791-14-6
Product Size:: 2mg

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