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Org 48762-0

Catalog No.
C007B-440052
Manufacturer No.
O286758-100mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

Org 48762-0 is a selective p38α and β kinase inhibitor (EC50 = 0.1 μM for p38α). Selective for p38α/β over a panel of 48 other human kinases. Inhibits LPS-induced TNFα release from PBMCs. Also inhibits cytokine release in an LPS-induced endotoxemia

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Org 48762-0 is a selective p38α and β kinase inhibitor (EC50 = 0.1 μM for p38α). Selective for p38α/β over a panel of 48 other human kinases. Inhibits LPS-induced TNFα release from PBMCs. Also inhibits cytokine release in an LPS-induced endotoxemia model in mice. Orally bioavailable.

Specifications and Purity: ≥98%

Molecular Formula: C24H16F2N4

Molecular Weight: 398.41

PubChem CID: 24822135

Isomeric SMILES: CN1C=C2C(=C(C(=NC2=N1)C3=CC=C(C=C3)F)C4=CC=NC=C4)C5=CC=C(C=C5)F

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/O286758-SCI_1292952930d114b02a24025937a9a032.pdf

UPC:
12141725
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
O286758-100mg
CAS:
755753-89-0
Product Size:
100mg

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