ONO-4059 analogue (C007B-397972)

Catalog No.: C007B-397972
Manufacturer No.: O421334-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationONO-4059 analogue ONO-4059 analogue (ONO-WG-307) is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.TargetsBTK 23.9 nMIn vitroIn TMD-8 cells, ONO-4059 inhibits cell growth with IC50 of 3.59 nM, and induces cell apoptosis. The combination of of ONO-4059 with doxorubicin, etoposide, vincristine or dexamethasone causes the increased apoptosis ratio.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C25H24N6O3

Molecular Weight: 456.5

PubChem CID: 89455219

Isomeric SMILES: C=CC(=O)N1CCC[C@@H](C1)N2C3=NC=NC(=C3N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5)N

UPC:: 85122002
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: O421334-1ml
CAS:: 1351635-67-0
Product Size:: 1ml

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