A hybrid molecule patterned after N-arachidonoyl serotonin inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 &muM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 &muM).
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A hybrid molecule patterned after N-arachidonoyl serotonin; inhibits capsaicin-induced TRPV1 channel activation (IC50 = 2.57 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM).
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