Biochem/physiol Actions Nutlin-3b, a (+)-enantiomer of Nutlin-3, is a weakly potent antagonist of p53/MDM2 (IC50 = 13.6 μ:M) that can serve as negative control for Nutlin-3a (IC50 = 90 nM) and other Mdm2 inhibitors.
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Nutlin-3b, a (+)-enantiomer of Nutlin-3, is a weakly potent antagonist of p53/MDM2 (IC50 = 13.6 μM) that can serve as negative control for Nutlin-3a (IC50 = 90 nM) and other Mdm2 inhibitors.
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