NU6140 is a selective CDK2-cyclin A inhibitor (IC50, 0.41 μM), exhibits 10- to 36-fold selectivity over other CDKs. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively. Enhances the apoptotic effect, with anti-cancer activity.
Specifications and Purity: ≥98%
Molecular Formula: C23H30N6O2
Molecular Weight: 422.52
PubChem CID: 10202471
Isomeric SMILES: CCN(CC)C(=O)C1=CC=C(C=C1)NC2=NC3=C(C(=N2)OCC4CCCCC4)NC=N3
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/N275662-SCI_d0a1e245449f3672e3320409eca6b660.pdf
- UPC:
- 41106006
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N275662-50mg
- CAS:
- 444723-13-1
- Product Size:
- 50mg
- Hazard Statement Codes:
- H341
- Precautionary Statement Codes:
- P281:P202:P201
akash.verma@cenmed.com
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