InformationNTP42 is a novel antagonist of thromboxane A2 (TXA2) receptor with IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609. NTP42 is currently in development for the treatment of pulmonary arterial hypertension (PAH).
Molecular Formula: C25H23F2N3O5S
Molecular Weight: 515.5
PubChem CID: 124147085
Isomeric SMILES: CC(C)(C)NC(=O)NS(=O)(=O)C1=C(C=CC(=C1)C#N)OC2=CC=CC(=C2)C3=CC=C(C=C3)OC(F)F
- UPC:
- 12142206
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N412560-5mg
- CAS:
- 2055599-51-2
- Product Size:
- 5mg
akash.verma@cenmed.com
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