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nsc 185058

NSC 185058 (C007B-392122)

Catalog No.
C007B-392122
Manufacturer No.
N413595-100mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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InformationNSC185058 inhibitsATG4B, the lipidation of LC3B, and autophagy without affecting the MTOR or PtdIns3K pathways.NSC185058 is an ATG4B antagonist. ATG4B stimulates autophagy by promoting autophagosome formation through reversible

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InformationNSC185058 inhibitsATG4B, the lipidation of LC3B, and autophagy without affecting the MTOR or PtdIns3K pathways.NSC185058 is an ATG4B antagonist. ATG4B stimulates autophagy by promoting autophagosome formation through reversible modification of ATG8. Inclusion of the ATG4B inhibitor NSC185058 enhances the anti-tumor activity of radiation therapy (RT). NSC185058 decreases glioblastoma (GBM) cell tumorigenicity, and enhances the anti-tumor activity of RT when applied to orthotopic GBM xenograft models.

Specifications and Purity: ≥98%

Molecular Formula: C11H9N3S

Molecular Weight: 215.27

PubChem CID: 750538

Isomeric SMILES: C1=CC=NC(=C1)C(=S)NC2=CC=CC=N2

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/N413595-SCI_ea2e7c62f50cb8d62abae8701e5ac555.pdf

UPC:
41114626
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
N413595-100mg
CAS:
39122-38-8
Product Size:
100mg
Hazard Statement Codes:
H335:H319:H315:H302
Precautionary Statement Codes:
P305+P351+P338:P261

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