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norleual tfa (c09-1157-638)

Norleual TFA (C007B-379371)

Catalog No.
C007B-379371
Manufacturer No.
N659268-1mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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Norleual TFA, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC 50 of 3 pM. Norleual TFA is an AT4 receptor antagonist and exhibits potent antiangiogenic activities.Appearance:SolidIn Vitro:/Norleual TFA

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Norleual TFA, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC 50 of 3 pM. Norleual TFA is an AT4 receptor antagonist and exhibits potent antiangiogenic activities.Appearance:SolidIn Vitro:/Norleual TFA at 20 and 50 pM significantly reduces HGF-dependent c-Met and Gab1 phosphorylation. 20 pM Norleual TFA dramatically reduces HGF-initiated association between Gab1 and c-Met in HEK293 cells. Norleual TFA markedly attenuates HGF-dependent c-MeIn Vivo:Norleual TFA (50 μg/kg; intraperitoneal injection; daily; for 2 weeks; C57BL/6 mice) suppresses pulmonary colonization by B16-F10 murine melanoma cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Biological Activity:Norleual TFA, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC 50 of 3 pM. Norleual TFA is an AT4 receptor antagonist and exhibits potent antiangiogenic activities.

Specifications and Purity: ≥99%

Molecular Formula: C43H59F3N8O9

Molecular Weight: 888.97

UPC:
51182010
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
N659268-1mg
Product Size:
1mg

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