General description
A potent antagonist highly selective for κ opioid receptor with no effect on µ- or &delta- opioid receptors. Widely used in studies related to pain, addition, anxiety, depression, and sleep.
Biochem/physiol Actions
Primary Target
kappa opioid receptor
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Kishioka, S., et al. 2013. Neurosci. Letters.In press.
Valdez, G., et al. 2012. Pharma. Biochem. and Behavior.102, 44.
Takemori AE et al. 1988. J. Pharmacol. Exp. Ther.246, 255.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Molecular Weight: 734.71. Empirical Formula: C40H43N3O6 · 2HCl. Assay: ≥. 98% (HPLC). Quality Level: 100. form: solid. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze, protect from light. color: white to off-white. solubility: water: 50 . mM. storage temp.: −. 20°C. InChI: 1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2. InChI key: GYEXSFKLGQBRBJ-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51101630
- Condition:
- New
- HazmatClass:
- No
- MPN:
- 5080170001
- CAS:
- 105618-26-6
akash.verma@cenmed.com
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