Biochem/physiol Actions
Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.
- UPC:
- 51111617
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SML0379-25MG
- CAS:
- 799264-47-4
akash.verma@cenmed.com
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