NGB 2904 is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor, with a Ki of 1.4 nM. NGB 2904 shows selectivity for D3 over D2, 5-HT2, α1, D4, D1 and D5 receptors (Kis=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 antagonizes Quinpirole-stimulated mitogenesis.
Specifictaions: Moligand™, ≥98%
MDL Number: C28H29Cl2N3O
Molecular Formula: 494.46
PubChem CID: 19366304
Isomeric SMILES: C1CN(CCN1CCCCNC(=O)C2=CC3=C(C=C2)C4=CC=CC=C4C3)C5=C(C(=CC=C5)Cl)Cl.Cl
- UPC:
- 42182008
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N612287-100mg
- CAS:
- 189060-98-8
- Product Size:
- 100mg
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