Netarsudil (AR-13324) 2HCl (C007B-392227)

Catalog No.: C007B-392227
Manufacturer No.: N413948-10mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationNetarsudil (AR-13324) 2HCl Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension.Targetsnorepinephrine transporter (NET) ; ROCK ; 2 nM(Ki)In vivoNetarsudil primarily targets cells in the conventional outflow tract, efficiently decreasing IOP in both human and non-human primate eyes. In addition, netarsudil has been shown to increase outflow facility in non-human primate eyes and to decrease episcleral venous pressure in rabbit eyes.

Specifications and Purity: ≥98%

Molecular Formula: C28H27N3O3.2HCl

Molecular Weight: 526.45

PubChem CID: 66599892

Isomeric SMILES: CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)[C@@H](CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.Cl.Cl

UPC:: 41111910
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: N413948-10mg
CAS:: 1253952-02-1
Product Size:: 10mg

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