NAS181 is a potent and selective antagonist of rat 5-HT1B receptor, with a Ki of 47 nM. NAS181 shows 13-fold selectivity for r5-HT1B over bovine 5-HT1B receptor (Ki=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT1B autoreceptors.
Specifications and Purity: ≥97%
Molecular Formula: C19H26N2O4•(CH4O3S)
Molecular Weight: 538.63
PubChem CID: 45073445
Isomeric SMILES: CS(=O)(=O)O.CS(=O)(=O)O.C1CO[C@H](CN1)COC2=CC=CC3=C2OCC(=C3)CN4CCOCC4
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/N288858-SCI_ef7eb92247af7b978fe2e968bf2db105.pdf
- UPC:
- 42201602
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N288858-25mg
- CAS:
- 1217474-40-2
- Product Size:
- 25mg
akash.verma@cenmed.com
(732) 447-1115





