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nami-a (c09-1156-571)

NAMI-A (C007B-378327)

Catalog No.
C007B-378327
Manufacturer No.
N646402-10mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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NAMI-A is a ruthenium-based drug characterised by the selective activity against tumour metastases, inhibits the adhesion and migration.In vitro: NAMI-A can significantly affect tumor cells with metastatic ability.The half lifetime of NAMI-A

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NAMI-A is a ruthenium-based drug characterised by the selective activity against tumour metastases, inhibits the adhesion and migration.In vitro: NAMI-A can significantly affect tumor cells with metastatic ability.The half lifetime of NAMI-A elimination from the lungs is longer than for liver, kidney, and primary tumor. NAMI-A bound to collagen is active on tumor cells as shown in vitro by an invasion test, using a modified Boyden chamber and Matrigel, and it inhibits the matrix metallo-proteinases MMP-2 and MMP-9 at micromolar concentrations.The ruthenium drug NAMI-A inhibits the adhesion and migration of colorectal cancer cells. NAMI-A decreases α5β1 integrin expression and FAK auto-phosphorylation on Tyr 397.In vivo: The reference for NAMI-A is 35 mg/kg/day.Form:Solid.

Specifications and Purity: ≥98%

Molecular Formula: C8H15Cl4N4ORuS

Molecular Weight: 458.18

PubChem CID: 133082692

Isomeric SMILES: CS(=O)C.C1=C[NH+]=CN1.C1=CN=CN1.[Cl-].[Cl-].[Cl-].[Cl-].[Ru+3]

UPC:
85000000
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
N646402-10mg
CAS:
201653-76-1
Product Size:
10mg

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