N N-DIISOPROPYLETHYLAMINE REAGENTPLUS(R) >=99% (C005B-058292)

General description

N,N-Diisopropylethylamine, also known as Hünig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed for substitution reactions. It acts as an activator for chiral iridium N, P ligand complexes, which can be utilized in the hydrogenation of α, β-unsaturated nitriles. The influence of varying concentration of N,N-diisopropylethylamine on the synthesis of olvanil in the presence of lipase catalyst has been investigated.

Application

N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides.

Proton scavenger used in peptide coupling, enolboration, Pd(0)-catalyzed alkoxycarbonylation of allyl phosphates and acetates, and as a catalyst in vinyl sulfone synthesis.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Molecular Weight: 129.24. Empirical Formula: C₈H₁₉N. linearFormula: [(CH₃)₂CH]₂NC₂H₅. vapor pressure: 31 mmHg ( 37.7 °C). Quality Level: 200. product line: ReagentPlus^®. . Assay: ≥. 99%. form: liquid. refractive index: n20/D 1.414 (lit.). bp: 127 . °C (lit.). mp: <. −. 50 . °C (lit.). density: 0.742 . g/mL . at 25 . °C (lit.). SMILES string: CCN(C(C)C)C(C)C. InChI: 1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3. InChI key: JGFZNNIVVJXRND-UHFFFAOYSA-N. Pictograms: GHS02,GHS05,GHS06,GHS09. Signal Word: Danger. Hazard Statements: H225 - H302 - H318 - H331 - H335 - H411. Precautionary Statements: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 3 - Flammable liquids. WGK: WGK 2. Flash Point(F): 49.1 °F. Flash Point(C): 9.5 °C.