N-arachidonoyl phosphatidylethanolamine (NAPE) is a precursor in anandamide (AEA) biosynthesis via multiple pathways (1). NAPE can be cleaved by a phospholipase D yielding phosphatidic acid and AEA (1,2). On the other hand, in macrophages NAPE is cleaved by a phospholipase C yielding phosphoanandamide (pAEA). A phosphatase, PTPN22 is one enzyme that cleaves pAEA leading to the generation of anandamide. Another pathway proceeds via double deacylation of NAPE generating glycerophospho-NAE. Phosphodiesterase-mediated cleavage of this intermediate yields anandamide.N-Arachidonoyl phosphatidylethanolamineis a precursor in anandamide biosynthesis.
Specifications and Purity: ≥97%
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/N380738-SCI_477751ef1921700b2a33a7cf240c5c26.pdf
- UPC:
- 51142611
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N380738-1mg
- Product Size:
- 1mg
- Precautionary Statement Codes:
- P264
akash.verma@cenmed.com
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