MYRIOCIN FROM MYCELIA STERILIA (C005B-454885)

Catalog No.: C005B-454885
Manufacturer No.: M1177-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Application Myriocin from Mycelia sterilia has been used as an inhibitor of sphingolipid or ceramide biosynthesis in various studies. Biochem/physiol Actions Myriocin from Mycelia sterilia is a fungal metabolite with potent

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Description
Specifications

Application

Myriocin from Mycelia sterilia has been used as an inhibitor of sphingolipid or ceramide biosynthesis in various studies.

Biochem/physiol Actions

Myriocin from Mycelia sterilia is a fungal metabolite with potent immunosuppressant activity. It inhibits serine palmitoyltransferase at picomolar concentrations blocking synthesis of ceramide, a precursor of sphingomyelin and glycosphingolipids. It disrupts substratum adhesion of melanoma cells. It has been suggested that its immunosuppressant activity in the cytotoxic T-cell line CTTL-2 is due to apoptosis induction.

UPC:: 42281803
Condition:: New
HazmatClass:: Yes
MPN:: M1177-25MG
CAS:: 35891-70-4

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