MYRICETIN >= 96.0% (HPLC) (C005B-046796)

General description

Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree.

Application

Myricetin has been used:

• to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in rats
• as a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP)
• to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicans
• as a reference standard for the quantification of phenolic compounds from Juniperus species

Biochem/physiol Actions

Myricetin exerts anti-oxidant effects, and anti-inflammatory effects by regulating multiple signal pathways. It also displays anti-diabetic and hepatoprotective effects. Myricetin strongly inhibits yeast α-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase. It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy. Myricetin also has various nutraceuticals values and therapeutic effects.

Molecular Weight: 318.24. Empirical Formula: C₁₅H₁₀O₈. Quality Level: 200. Assay: ≥. 96.0% (HPLC). form: powder. mp: ≥. 300 . °C, >. 300 . °C (lit.). solubility: ethanol: 10 . mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow. application(s): metabolomics
vitamins, nutraceuticals, and natural products. SMILES string: Oc1cc(O)c2C(: O)C(O): C(Oc2c1)c3cc(O)c(O)c(O)c3. InChI: 1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H. InChI key: IKMDFBPHZNJCSN-UHFFFAOYSA-N. Gene Information: human ... CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).