General description
MSTFA (N-Methyl-N-trimethylsilylfluoroacetamide) is an important trimethylsilyl reagent, and a commonly applied reagent since it is highly reactive towards a broad range of compound classes. GC-MS optimization studies reveal the use of this reagent either alone or in combination with 1% of trimethylchlorosilane as a catalyst for silylation of complex mixtures. It has similar reactivity as BSA and BSTFA.
Application
MSTFA reagent may be used as a derivatizing agent in the following:
- Analysis of estrogen steroids such as estrone (E1), 17α-ethinylestradiol (EE2), and trenbolone acetate metabolites, melengestrol in environmental matrices using gas chromatography coupled to mass spectrometry (GC-MS).
- Quantification of ibuprofen, naproxen, ketoprofen, and diclofenac in wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).
Features and Benefits
- Very volatile of TMS-acetamides.
- More volatile than BSA or BSTFA but with similar silylation strength.
- Useful in the analysis of volatile trace materials.
- Used in the preparation of volatile and thermally stable derivatives for GC and MS analysis.
Legal Information
CERILLIANT is a registered trademark of Cerilliant Corporation
- UPC:
- 42293134
- Condition:
- New
- HazmatClass:
- Yes
- MPN:
- M-132-10X1.2ML
- CAS:
- 24589-78-4
akash.verma@cenmed.com
(732) 447-1115





