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monoamine oxidase b human (c15-1890-181)

MONOAMINE OXIDASE B HUMAN RECOMBINANT EXPRESSED IN BACULOVIRUS INFECTED BTI INSECT CELLS (C005B-453529)

Catalog No.
C005B-453529
Manufacturer No.
M7441-5X1VL
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
EA

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General description Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs. Application Drugs that inhibit monoamine oxidase B activity are used for the treatment of

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General description

Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.

Application

Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression.

Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.

Biochem/physiol Actions

MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.

Unit Definition

kynuramine deamination activity: One unit will deaminate 1 nanomole of kynuramine per minute at pH 7.4 at 37 deg C.

UPC:
51131510
Condition:
New
HazmatClass:
No
MPN:
M7441-5X1VL
Temperature Control Device:
Yes

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