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Mofegiline hydrochloride (C007B-439828)

Catalog No.
C007B-439828
Manufacturer No.
M339862-100mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

Mofegiline hydrochloride (MDL-72,974) is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) and amine oxidase, copper containing 3 (AOC3) or vascular adhesion protein 1 (VAP-1), also known as semicarbazide-sensitive amine oxidase

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Mofegiline hydrochloride (MDL-72,974) is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) and amine oxidase, copper containing 3 (AOC3) or vascular adhesion protein 1 (VAP-1), also known as semicarbazide-sensitive amine oxidase (SSAO). Mofegiline hydrochloride demonstrates a time dependent irreversible inhibition of SSAO. In rat studies, Mofegiline hydrochloride showed preferential inhibition of brain MAO-B with ED50 values of 8 and 0.18 mg/kg p.o. for the A and B forms, respectively. In anaesthetized rats, Mofegiline hydrochloride did not significantly potentiate tyramine effects on the cardiovascular system. Mofegiline hydrochloride was studied and extensively researched as a potential treatment of Parkinson′s disease and Alzheimer′s disease, but was never marketed.

Specifications and Purity: ≥97%

Molecular Formula: C11H13F2N•HCl

Molecular Weight: 233.69

PubChem CID: 6446650

Isomeric SMILES: C1=CC(=CC=C1CC/C(=C/F)/CN)F.Cl

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/M339862-SCI_c8e1819ccd6fb7718e9200b15dd87c06.pdf

UPC:
51101510
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
M339862-100mg
CAS:
120635-25-8
Product Size:
100mg
Hazard Statement Codes:
H335:H319:H302
Precautionary Statement Codes:
P280:P271:P270:P264:P261

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