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MMAF sodium (C007B-374942)

Catalog No.
C007B-374942
Manufacturer No.
M650064-10mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates ( ADC s) such

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MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates ( ADC s) such as Vorsetuzumab mafodotin and SGN-CD19AIn VitroMMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC 50 s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Auristatin.

Specifications and Purity: ≥99%

Molecular Formula: C39H64N5NaO8

Molecular Weight: 753.94

PubChem CID: 139035010

UPC:
12141806
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
M650064-10mg
CAS:
1799706-65-2
Product Size:
10mg

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