MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates ( ADC s) such as Vorsetuzumab mafodotin and SGN-CD19AIn VitroMMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC 50 s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Auristatin.
Specifications and Purity: ≥99%
Molecular Formula: C39H64N5NaO8
Molecular Weight: 753.94
PubChem CID: 139035010
- UPC:
- 12141806
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M650064-10mg
- CAS:
- 1799706-65-2
- Product Size:
- 10mg
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