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MLS-0437605 (C007B-374134)

Catalog No.
C007B-374134
Manufacturer No.
M646706-10mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

MLS-0437605 is a selective dual-specificity phosphatase 3 (DUSP3) inhibitor with an IC 50 of 3.7 μM. MLS-0437605 is more selective for DUSP3 than DUSP22 and other protein tyrosine phosphatases (PTPs).In VitroMLS-0437605 efficiently inhibits platelet

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MLS-0437605 is a selective dual-specificity phosphatase 3 (DUSP3) inhibitor with an IC 50 of 3.7 μM. MLS-0437605 is more selective for DUSP3 than DUSP22 and other protein tyrosine phosphatases (PTPs).In VitroMLS-0437605 efficiently inhibits platelet aggregation in response to collagen related peptide (CRP) and rhodocytin, but not after stimulation with thromboxane. MLS-0437605 causes a decrease in pY of a ~70-kDa band after stimulation with CRP or rhodocytin. Tyrosine phosphorylation of immunoprecipitated Syk and PLCγ2 is also reduced by MLS-0437605. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid.

Specifications and Purity: ≥99%

Molecular Formula: C16H11FN4O2S

Molecular Weight: 342.35

UPC:
41113643
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
M646706-10mg
CAS:
862975-18-6
Product Size:
10mg

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