A noncompetitive, allosteric inhibitor of Cdc42 (EC50 = 2.1 µM) with no inhibitory action against Rho, Ras, Rab, or Rac also inhibits the constitutively active Cdc42 Q61L mutant (EC50 = 2.6 µM).
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A noncompetitive, allosteric inhibitor of Cdc42 (EC50 = 2.1 µM) with no inhibitory action against Rho, Ras, Rab, or Rac; also inhibits the constitutively active Cdc42 Q61L mutant (EC50 = 2.6 µM).
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