akash.verma@cenmed.com
(732) 447-1115
ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC 50 of 40 nM.In VitroML-109 (Compound 2) is a full agonist at TSHR with an EC 50 of 40 nM and, like compound 1, it has no activity at FSHR or LHCGR. ML-109 contains an aminal, a functional group that is subject to hydrolysis and/or other degradation mechanisms. ML-109 is surprisingly stable at neutral and basic conditions (t 1/2 of ~16 h) but is found to degrade at low pH (t 1/2 of ~3 h). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:EC50: 40 nM (TSHR).
Specifications and Purity: ≥99%
Molecular Formula: C31H29N3O5
Molecular Weight: 523.58
PubChem CID: 25246343
Isomeric SMILES: CC(=O)NC1=CC=C(C=C1)OCC2=C(C=CC(=C2)C3NC4=C(C(=CC=C4)O)C(=O)N3CC5=CC=CC=C5)OC
- UPC:
- 42181514
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M651343-25mg
- CAS:
- 1186649-91-1
- Product Size:
- 25mg
