MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family .In VivoMKC-1 (200 mg/kg, orally, daily) significantly increased the median survival time (MST) of mice bearing Caki-1 renal cell xenograft tumors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C22H16N4O4
Molecular Weight: 400.39
- UPC:
- 12141730
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M655611-1ml
- CAS:
- 125313-92-0
- Product Size:
- 1ml
akash.verma@cenmed.com
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