Mito-TEMPO (C007B-231397)

Catalog No.: C007B-231397
Manufacturer No.: M421267-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

InformationMito-TEMPO Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced RIP3 kinase expression.TargetsRIP3 kinaseIn vitroMito-TEMPO improves blastocyst development by superoxide reduction in porcine embryos in vitro.In vivoMito-Tempo (MT) treatment inhibits APAP-induced RIP3 kinase expression, and RIP3-deficient mice shows caspase activation and apoptotic morphology in hepatocytes analogous to MT treatment.Cell Research(from reference)Cell lines：Porcine embryos Concentrations：0.1/u2009μM.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C29H36ClN2O2P

Molecular Weight: 511

PubChem CID: 134828258

UPC:: 12141803
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: M421267-1ml
CAS:: 1334850-99-5
Product Size:: 1ml

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