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mission(r) esirna (c15-1376-454)

MISSION ESIRNA HUMAN CHAF1A (ESIRNA1) (C005B-133651)

Catalog No.
C005B-133651
Manufacturer No.
EHU084491-50UG
Manufacturer Name
Sigma-Aldrich
Quantity
50
Unit of Measure
UG

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MISSION ® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence.

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General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Biochem/physiol Actions

CHAF1A (chromatin assembly factor 1 subunit A) is one of the subunits of CAF1 complex, a histone chaperone responsible for the positioning of histone H3 and H4 dimers into nucleosomes. CAF1 is needed for S-phase progression, heterochromatin formation and chromatin restoration after DNA repair. CAF1A is required for promoting protein and chromosome associations with nucleoli. It is required for cell proliferation and is upregulated in colon cancer and aggressive neuroblastoma.

Legal Information

MISSION is a registered trademark of Sigma-Aldrich Co. LLC

description: Powered by Eupheria Biotech. Quality Level: 100. product line: MISSION®. . form: lyophilized powder. esiRNA cDNA target sequence: GCCTGAATCTTGTCCCAAAGGGGAAAGCCGATGACATGTCAGACGATCAGGGTACTTCTGTGCAAAGTAAAAGCCCCGATTTAGAGGCCTCTTTGGACACCTTGGAAAACAACTGTCATGTGGGTTCTGACATAGACTTTAGACCGAAACTTGTCAACGGGAAGGGTCCCTTAGATAACTTTTTAAGAAATAGAATCGAAACCAGTATTGGCCAGAGCACAGTCATCATTGATTTGACAGAGGACTCGAATGAGCAGCCAGACAGTCTTGTGGACCACAATAAACTAAATTCTGAAGCCTCTCCCTCCAGGGAGGCAATAAATGGCCAGCGAGAAGACACTGGGGATCAGCAGGGGTTGTTGAAGGCCATTCAGAACGACAAGTTGGCATTTCCTGGAGAGA. Ensembl | human accession no.: ENSG00000167670. NCBI accession no.: NM_005483. shipped in: ambient. storage temp.: −. 20°C. Gene Information: human ... CHAF1A(10036), CHAF1A(10036). Storage Class Code: 10 - Combustible liquids. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
42202202
Condition:
New
HazmatClass:
No
MPN:
EHU084491-50UG
Temperature Control Device:
Yes

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