Mifamurtide TFA

Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA, an orphan agent, is a specific ligand of NOD2 used as an insAppearance:SolidIC50& Target:NOD2In Vitro:Mifamurtide TFA (MTP-PE TFA; 100 µM) induces a reduction of MG63 cells number when co-cultured with macrophages. Mifamurtide TFA (100 µM) increases both the M1 polarization marker iNOS and the M2 polarization marker CD206 mRNAs; both pro-inflammatoryIn Vivo:Mifamurtide TFA (MTP-PE TFA; 1mg/kg; i.v.; twice per week for 4 weeks) causes a trend of diminished spontaneous lung metastasis dissemination. Mifamurtide TFA (50 μg/mouse) improves glucose tolerance during endotoxemia in mice. Mifamurtide TFA (equiBiological Activity:Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA, an orphan agent, is a specific ligand of NOD2 used as an ins.

Specifications and Purity: ≥98%

Molecular Formula: C61H110F3N6O21P

Molecular Weight: 1351.52