MICROSOMES FROM LIVER POOLED FROM FEMALE RAT (SPRAGUE-DAWLEY) (C005B-453146)

Catalog No.: C005B-453146
Manufacturer No.: M9191-1VL
Manufacturer Name: Sigma-Aldrich
Quantity: 1
Unit of Measure: VL

Biochem/physiol Actions Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450.

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Description
Specifications

Biochem/physiol Actions

Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.

Unit Definition

One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C.
7-ethoxyresorufin O-deethylase activity: One unit will hydroxylate 1.0 picomole paclitaxel per minute at pH 7.4 at 37 deg C.

UPC:: 12161701
Condition:: New
HazmatClass:: No
MPN:: M9191-1VL
Temperature Control Device:: Yes

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