Microcystin-WR

Product introduction：Microcystins (MCs) are hepatotoxic cyclic heptapeptides, produced by various cyanobacterial species. MC’s cause adverse effects on freshwater systems with algae blooms.Microcystin WR contains tryptophane (W) in position 2 and arginine (R) in position 4.Microcystins are potent inhibitors of protein phosphatase types 1 and 2A (IC50 value of MC-WR for inhibiting PP2A = 0.18 nM). No effects on protein kinases are known. MCs are known to be hepatic tumor promoters in experimental animal models.

Specifications and Purity: 10ug/ml in methanol

Molecular Formula: C54H73N11O12

Molecular Weight: 1068.22

PubChem CID: 101619976

Isomeric SMILES: C[C@H]1[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)C(=C)N(C(=O)CC[C@@H](NC1=O)C(=O)O)C)C)CC2=CNC3=CC=CC=C32)C(=O)O)C)CCCN=C(N)N)/C=C/C(=C/[C@H](C)[C@H](CC4=CC=CC=C4)OC)/C