General description
(-)-Menthol is a monoterpene.
Application
(-)-Menthol may be used to synthesize:
- chiral enantiopure 2-(1-hydroxyalkyl)pyridines, which can react with phosphorus oxychloride to form C3-symmetric tripodal ligands
- menthylphosphorodichioridite, a chiral derivatizing agent for the determination of enantiomeric purity of chiral diols or diamines by 31P NMR spectroscopy
- (2R,4S)-2,3,4,5-tetrahydro-2-(-)-menthyloxy-2-methyl-4-phenylpyrano-[3,2-c]-benzopyran-5-one, an intermediate to prepare a warfarin analog
It may also be used as a chiral auxiliary, to induce chirality while synthesizing (-)-horsfiline.
Molecular Weight: 156.27. Empirical Formula: C
10H
20O. grade: puriss.. Quality Level: 200. Assay: 98.0-102.0%. form: solid. optical activity: [α. ]20/D −. 48 to −. 51°, c : . 10% in ethanol. quality: meets analytical specification of Ph. Eur., BP, USP. impurities: acidity or alcalinity, complies, related subst., complies, ≤. 0.05% non-volatile matter. mp: 41-44 . °C. suitability: in accordance for appearance of solution. application(s): pharmaceutical (small molecule). SMILES string: CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O. InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1. InChI key: NOOLISFMXDJSKH-KXUCPTDWSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319. Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): 201.2 °F - closed cup. Flash Point(C): 94 °C - closed cup. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.