CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI: SI = IC50 COX-1/IC50 COX-2) of >:500,000. (The COX-1 IC50 is >:500 mM, and COX-2 IC50 is <:1 nM.) As a reference point,
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI: SI = IC50 COX-1/IC50 COX-2) of >:500,000. (The COX-1 IC50 is >:500 mM, and COX-2 IC50 is <:1 nM.) As a reference point,
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI: SI = IC50 COX-1/IC50 COX-2) of >:500,000. (The COX-1 IC50 is >:500 mM, and COX-2 IC50 is <:1 nM.) As a reference point,
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI: SI = IC50 COX-1/IC50 COX-2) of >:500,000. (The COX-1 IC50 is >:500 mM, and COX-2 IC50 is <:1 nM.) As a reference point,
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI: SI = IC50 COX-1/IC50 COX-2) of >:500,000. (The COX-1 IC50 is >:500 mM, and COX-2 IC50 is <:1 nM.) As a reference point,
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI: SI = IC50 COX-1/IC50 COX-2) of >:500,000. (The COX-1 IC50 is >:500 mM, and COX-2 IC50 is <:1 nM.) As a reference point,
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells ( IC 50 of 3.0
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor with an IC 50 of 11.1 μM. RI(dl)-2 TFA does not influence RAD51 binding to ssDNA and inhibits homologous recombination (HR) activity in human cells ( IC 50 of 3.0
CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and
CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and
CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and
CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and
CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and
CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and