CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP|2|receptor antagonist (K|i = 10 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. In humans, CRTH2/DP2 is expressed on eosinophils, basophils and Th2 cells where it mediates the chemotactic activity of PGD2.
Specifications and Purity: ≥97%
Molecular Formula: C20H13Cl2FN2O5
Molecular Weight: 451.23
PubChem CID: 15949395
Isomeric SMILES: C1C(=O)N(C(=O)C12C3=C(C=CC(=C3)Cl)N(C2=O)CC(=O)O)CC4=C(C=CC(=C4)Cl)F
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/C344312-SCI_2c1774f844e29c3cb737baec296681d8.pdf
- UPC:
- 42192208
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C344312-1mg
- CAS:
- 916047-16-0
- Product Size:
- 1mg
- Precautionary Statement Codes:
- P264
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