Biochem/physiol Actions GeA-69 is a selective allosteric inhibitor of macrodomain 2 of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14), an anti-apoptotic pro-survival protein associated with inflammatory diseases and several types of
Biochem/physiol Actions GeA-69 is a selective allosteric inhibitor of macrodomain 2 of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14), an anti-apoptotic pro-survival protein associated with inflammatory diseases and several types of
Biochem/physiol Actions SGC6870 is a potent and selective protein arginine methyltransferase PRMT6 inhibitor (IC 50 = 77 nM by cell-free assays: IC 50 = 0.8 μ:M against asymmetric H3R2 dimethylation of overexpressed PRMT6 in HEK293T cells)
Biochem/physiol Actions SGC6870 is a potent and selective protein arginine methyltransferase PRMT6 inhibitor (IC 50 = 77 nM by cell-free assays: IC 50 = 0.8 μ:M against asymmetric H3R2 dimethylation of overexpressed PRMT6 in HEK293T cells)
Biochem/physiol Actions SGC6870 is a potent and selective protein arginine methyltransferase PRMT6 inhibitor (IC 50 = 77 nM by cell-free assays: IC 50 = 0.8 μ:M against asymmetric H3R2 dimethylation of overexpressed PRMT6 in HEK293T cells)
Biochem/physiol Actions SGC6870 is a potent and selective protein arginine methyltransferase PRMT6 inhibitor (IC 50 = 77 nM by cell-free assays: IC 50 = 0.8 μ:M against asymmetric H3R2 dimethylation of overexpressed PRMT6 in HEK293T cells)
Cell Line Origin Mouse neuroblastoma x Rat glioma hybrid Cell Line Description A 6-thioguanine resistant mutant of 108CC5 (Sigma Catalogue number 08062521), a mouse neuroblastoma N18TG2 x rat glioma C6-BU-1 hybrid Application Used as a
Cell Line Origin Mouse neuroblastoma x Rat glioma hybrid Cell Line Description A 6-thioguanine resistant mutant of 108CC5 (Sigma Catalogue number 08062521), a mouse neuroblastoma N18TG2 x rat glioma C6-BU-1 hybrid Application Used as a