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mbx-102

MBX-102

Catalog No.
C005B-313833
Manufacturer No.
SML0064-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG

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Application MBX-102 may be used in PPAR-mediated cell signaling studies. Biochem/physiol Actions MBX-102 has a potent transrepression effect on PPARγ:.

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Application

MBX-102 may be used in PPAR-mediated cell signaling studies.

Biochem/physiol Actions

MBX-102 has a potent transrepression effect on PPARγ. It is an oral glucose-reducing agent and also has insulin-sensitizing properties. It is useful as treatment for type 2 diabetes. MBX-102 also lowers triglycerides in a PPARα-independent manner.

MBX-102 is a selective PPAR modulator (SPPARM) and has been shown to inhibit phosphorylation of PPARγ. MBX-102 is converted to the active form, MBX-102 acid, in vivo.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Nuclear Receptors (Non-Steroids) and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

UPC:
42202002
Condition:
New
HazmatClass:
No
MPN:
SML0064-5MG
CAS:
24136-23-0

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