Maytansine is a potent microtubule-targeted compound that inhibits proliferation of cells at mitosis. Antibody-maytansinoid conjugates consisting of maytansinoids (DM1 and DM4) attached to tumor-specific antibodies have shown promising clinical results.The microtubule-targeting maytansinoids accumulate in cells and induce mitotic arrest at 250- to 1000-fold lower concentrations than those required for their association with tubulin or microtubules.
Specifications and Purity: ≥98%
Molecular Formula: C28H37ClN2O8
Molecular Weight: 565.05
PubChem CID: 9915934
Isomeric SMILES: C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)O)C)/C)OC)(NC(=O)O2)O
- UPC:
- 51111820
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M596354-50mg
- CAS:
- 57103-68-1
- Product Size:
- 50mg
akash.verma@cenmed.com
(732) 447-1115





