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mal-dpeg(r)24-nhs ester

MAL-DPEG(R)24-NHS ESTER

Catalog No.
C005B-432221
Manufacturer No.
QBD10314-100MG
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
MG

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Features and Benefits MAL-dPEG ®: 24 -NHS ester is a heterobifunctional, linear crosslinking reagents containing a maleimide group on one end of the single molecular weight dPEG ®: spacer arm and an amine-reactive active ester on the

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Features and Benefits

MAL-dPEG® 24-NHS ester is a heterobifunctional, linear crosslinking reagents containing a maleimide group on one end of the single molecular weight dPEG® spacer arm and an amine-reactive active ester on the other end. The number following the dPEG® refers to the exact number of spacer units present in the spacer arm. The maleimide group reacts readily and specifically with free sulfhydryl groups in aqueous media at pH 6.5-7.5. N-hydroxysuccinimide (NHS) ester are used widely in reactions with primary amines. The NHS-amine reactions can be carried out in aqueous or organic solvent. The dPEG® spacer is hydrophilic and non-immunogenic. Because it is a single molecular weight product, it gives the user precise spatial control. The dPEG® spacer also improves water solubility, decreases immunogenicity, and increases the hydrodynamic volume of the conjugate. The increased hydrodynamic volume results in longer serum half-life in vivo.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

UPC:
51131507
Condition:
New
HazmatClass:
No
MPN:
QBD10314-100MG

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