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m-dpeg(r)37-nhs ester

M-DPEG(R)37-NHS ESTER

Catalog No.
C005B-432112
Manufacturer No.
QBD10910-100MG
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
MG

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Features and Benefits m -dPEG 37 -NHS ester is a methyl-terminated, single molecular weight, discrete chain length polyethylene glycol (dPEG) spacer. The carboxylic acid moiety on the end of the molecule opposite the methyl cap is activated with

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Features and Benefits

m-dPEG37-NHS ester is a methyl-terminated, single molecular weight, discrete chain length polyethylene glycol (dPEG) spacer. The carboxylic acid moiety on the end of the molecule opposite the methyl cap is activated with N-hydroxysuccinimide (NHS) for facile reaction with free amines. The dPEG spacer is 112 atoms (133.9 Ã…) long, a monodisperse equivalent of a polymeric PEG1500. m-dPEG37-NHS ester can be used to modify silica shelled quantum dots to make them water-soluble. Also, it has been employed to improve the pharmacokinetic (PK) and biodistribution (BD) properties of an antibody. Carbon nanotubes and inorganic nanoparticles with amine-functionalized surfaces could also be modified to passivate the surface and make it hydrophilic. Overall, proteins and other biomolecules conjugated to this product will have higher water solubility, reduced or eliminated antigenicity, and improved PK and BD properties.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

UPC:
51111707
Condition:
New
HazmatClass:
No
MPN:
QBD10910-100MG

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