LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity ( EC 50 =3 nM)In VitroIn HEK293 cells transiently expressing human, dog, rhesus monkey, and mouse D1 receptors, the EC 50 s of LY3154207 are 2.3 nM, 2.0 nM, 2.5 nM, and 62.1 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:EC50: 3 nM (human dopamine D1 receptor).
Specifications and Purity: ≥99%
Molecular Formula: C24H29Cl2NO3
Molecular Weight: 450.40
PubChem CID: 86290953
Isomeric SMILES: C[C@H]1C2=CC=CC(=C2C[C@@H](N1C(=O)CC3=C(C=CC=C3Cl)Cl)CO)CCC(C)(C)O
- UPC:
- 41104704
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L651647-50mg
- CAS:
- 1638667-79-4
- Product Size:
- 50mg
akash.verma@cenmed.com
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