LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40) , with EC 50 s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1 , is potential for the treatment of type 2 diabetes mellitus (T2DM)Form:SolidIC50& Target:EC50:7 nM (human GPR40), 1 nM (mouse GPR40), 3 nM (rat GPR40).
Specifications and Purity: ≥99%
Molecular Formula: C28H29NO4S
Molecular Weight: 475.60
PubChem CID: 71257551
Isomeric SMILES: CC#C[C@@H](CC(=O)O)C1=CC=C(C=C1)OCC2=CC=C(S2)CN3CCCC4=C3C(=CC=C4)OC
- UPC:
- 41103308
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L647237-100mg
- CAS:
- 1423018-12-5
- Product Size:
- 100mg
akash.verma@cenmed.com
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